Are we proof that a new drug to stop type 1 diabetes really does work?

A new drug for Type 1 diabetes, Teplizumab, is being tested in the PROTECT clinical trial.

Teplizumab blocks the action of insulin-destroying antibodies in type 1.

Read the article on the Daily Mail

The ELSA Study

The ELSA study launched nationally on World Diabetes Day in November 2022. Within 24 hours, over 1000 children were signed-up to the study! By February 2023, we have sent over 3000 home-testing kits out to families and have analysed over 1000 kits so far. The next phase of the study is to disseminate to schools and general practices across the UK. A huge thank you to the parents and children who have taken part in the ELSA study. If you would like to find out more about screening your child for type 1 diabetes, visit: https://www.elsadiabetes.nhs.uk/.

Readily Available Drug Shows Promise in Treating Type 1 Diabetes

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Study shows verapamil can have a beneficial effect on the pancreas in children with newly diagnosed type 1 diabetes.

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First Treatment to Delay Type 1 Diabetes Licensed in the US

A Doctor Checking a Child

On 17/11/22 teplizumab was approved by the US Food and Drug Administration (FDA) as the first ever treatment indicated to delay the onset of stage 3 type 1 diabetes. This is the biggest treatment breakthrough for the condition since the discovery of insulin 100 years ago.

Although teplizumab is not approved in the UK yet, the US approval paves the way for this life-changing treatment to be made available to people at high risk of developing type 1 diabetes in the UK too.

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Type 1 Diabetes Breakthrough

Scientists and researchers are hoping to slow down the progression or prevent type one diabetes with immunotherapy treatments. This thought-provoking article from  DUK’s Balance magazine explains how immunotherapy can help fight type 1 diabetes.

Delaying type 1 diabetes: an exciting breakthrough has been made by scientists in the trial of an immunotherapy drug that has been shown to delay a diagnosis of type 1 diabetes.

Preserving Insulin production in people with newly diagnosed type 1 diabetes: progress made with drug aiming to boost insulin production in newly diagnosed type 1’s.

Multi-peptide Trial Aims to ‘Stall’ Type 1 Diabetes

Researchers at King’s College London and Guy’s and St Thomas’ hospital look into the possibility of slowing the progression of type 1 diabetes.

Link to news article with video:  http://www.bbc.co.uk/news/health-35847271

Pioneering Research for Type 1 Diabetes

MonoPepT1De clinical trial for type 1 diabetes treatment shows promising results.

Link to news article: http://www.bbc.co.uk/news/health-40876438

Link to publication of results: http://stm.sciencemag.org/content/9/402/eaaf7779.full