Schedule

January 27^th 1-2pm

• Rabbi Swaby (University of Oxford): Testing to predict stage 3 type 1 diabetes
• Katie Boest Bjerg (Cardiff University): Time of day changes in the NOD mouse model of T1D

We are looking for some ECRs to present Journal Clubs on some of the recent trials in T1D. If you are an ECR who is interested or if you would like to volunteer an ECR, we’d love to hear from you!

For more information and the zoom link please contact Anna.Long@bristol.ac.uk or J.Boldison@exeter.ac.uk and M.Russell@exeter.ac.uk.

Brief information on the session types

The meetings will take place monthly. Sessions will be a mix of ‘Two 20-minute talks with discussion time’, a quarterly ‘Themed session’ or a Plenary Single speaker session.

The sessions alternate between Monday 1-2pm and Tuesday 3-4pm.

Speaker instructions:

• 20-minute talks with ~ 10 mins for discussion
• There is no pressure to fill the time
• Please include an introduction for a general type 1 diabetes audience. We have plenty of postgraduate students, so please aim your talk at a level understandable to them.
• The group includes a mix of researchers, but we are all doing some research related to type 1 diabetes. It includes research active clinicians, immunologists, cell biologists, and data scientists. So please ensure you are pitching your talk to make it accessible to all.

Research updates from T1D EgG team members:

New research, published in the journal, Diabetic Medicine, has revealed that children who develop type 1 diabetes (T1D) under the age of 12 activate genes involved in immune responses that does not occur in people who develop the disease at an older age. Identification of these differentially expressed genes associated with lymphocyte differentiation, activation and migration in the pancreas of young people developing diabetes is helping us to better understand disease endotypes, which remains key to targeting of appropriate disease-modifying interventions. The paper is available to read online: https://onlinelibrary.wiley.com/doi/full/10.1111/dme.15155

Previous Presentations

Kathleen Gillespie – University of Bristol: 1 year of the Type 1 Diabetes Risk in Adults (T1DRA) study

Sarah Richardson – University of Exeter: Leveraging new knowledge from the human pancreas to advance and improve understanding and treatment of Type 1 diabetes.

Mark Russell – University of Exeter: JAK inhibitors as a treatment for type 1 diabetes; exploring the evidence

Dr Rebecca Dewhurst-Trigg (University of Exeter) – Exploring the islet-protective role of native human pancreatic mesenchymal stromal cells in health and type 1 diabetes

Please if you have any recent papers that you would like to have advertised to the T1D EgG team, let us know and we can post a link here.