USTEKID Study
Recruitment closed
10/09/2021
Summary
Trial of a new medication in people with Type 1 diabetes aged 12-18 and within 100 days of diagnosis.
Aim
To investigate whether this medication can delay or halt the damage to the pancreas of people recently diagnosed with type 1 diabetes, making it easier to achieve optimal diabetes control in the early years following diagnosis.
If you are interested in taking part, please click the “Get Involved” button below:
Eligibility to take part
- Age 12-18 years
- Diagnosed with type 1 diabetes in the last 100 days
- Commenced on insulin within 1 month of diagnosis
- Body weight < 100kg
- Evidence of body still making some insulin
- Able and willing to record data for the study
What will I be asked to do?
We will ask you to agree to being tested to see if your body is still making some insulin on its own. If it is, we can include you in the study and give you the study drug or a placebo (dummy medicine). You will have injections of the study medicine or placebo 7 times over 44 weeks. You will also be asked to provide blood and urine samples at study visits and you will be asked to complete three short questionnaires.
If you are aged between 12-15, your parent/carer will be asked to agree to you taking part.
Who is running this study?
This study is being run by Cardiff University and Swansea University. It is funded by the National Institute of Health Research Efficiency and Mechanism Evaluation (NIHR EME) programme. The hospitals listed below will be participating in the study:
Hospitals taking part so far:
- University Hospital of Wales, CARDIFF
- Noah’s Ark Children’s Hospital for Wales, CARDIFF
- Tayside Children’s Hospital, DUNDEE
- Royal Devon and Exeter Hospital, EXETER
- Royal Aberdeen Children’s Hospital, ABERDEEN
- Morriston Hospital, SWANSEA
- Leicester Royal Infirmary, LEICESTER
- St George’s Hospital, LONDON
- St James University Hospital, LEEDS
- Royal Alexandra Children’s Hospital, BRIGHTON
- The Royal London Hospital (Barts), LONDON
- Norfolk and Norwich University Hospital, NORWICH
- Evelina children’s hospital, LONDON
- Countess of Chester Hospital, CHESTER
Site Locator
External Links
Funded by the National Institute of Health Research Efficacy and Mechanism Evaluation (NIHR EME) programme.
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Getting close to reaching the end of the trial data collection period now! Last participant visit is due Sept 2022, then all hands on deck to start analysis! @STU_Swan @T1D_UK @DRG_Swansea
For anyone following the trial's progress, we've recruited all 72 participants needed and 43 of 45 have completed their week 52 follow up so far. On target to finish Sept 2022 thanks to our amazing sites and the commitment of the participants and their parents
It's been a great collaboration and hopefully there'll be many more. Thanks for your excellent advice Ash!
